Research Technician (Cell Culture)

18th November 2021

Engitix uses proprietary decellularisation technologies to expand cells in 3D culture. Unlike traditional decellularisation technologies which generate extracellular matrix (ECM) products from animal tissue, the Engitix 3D Tissue Engineering System produces human ECM scaffolds which retain the biophysical and biochemical properties of the healthy or diseased donor organ ECM. These ECM scaffolds are then used to develop in vitro disease models for the discovery and validation of novel therapeutic targets and to identify effective therapeutics for fibrosis and solid tumours.

Key Responsibilities

The post holder will be responsible for the maintenance of multiple primary and immortal cells according to standard operating procedures and the organization of cell culture facilities, providing technical support to the scientific team. This is a scientific support role and will involve routine tasks that will suit a candidate who has previous experience of working with cells within a lab/company environment.  Key responsibilities will include:

  • Maintaining cell cultures in accordance with established SOPs and according to the needs of the research teams
  • Keeping the cell culture facility clean, tidy and organized as to minimise contamination risks at all times
  • Ensuring efficient running of the cell culture facility including preparing culture media and stock solutions, and monitoring consumption of cell culture facility consumables
  • Preparing cells for routine testing of mycoplasma infection and cell authentication
  • Maintaining excellent cell culture documentation and managing frozen cell culture stocks
  • Performing any other reasonable duties, as required

Qualifications and Competencies

Required

  • A BSc with experience in Biomedical sciences, Biochemistry, Biotechnology or related disciplines
  • At least 2 years’ industry experience performing laboratory research in either a biotech/pharma or CRO environment
  • Excellent aseptic technique and extensive relevant technical knowledge on cell culture (primary cells and cell lines) is required
  • The post holder is expected to be a strong team player with excellent communication skills (both written and verbal), work ethic and attention to detail
  • Good time-management skills and ability to work towards set deadlines
  • The post holder should be good at troubleshooting, methodical, well organised, and able to pay close attention to detail, particularly with regards to record keeping
  • Expected to work independently liaising closely with colleagues within and across functional groups to ensure deadlines are met
  • Due to the nature of the role, the requirement is for this position is to be lab based, office hours, five days per week

Desirable

  • Experience in multi-cellular and/or 3D culture systems would be highly advantageous
  • Experience of two or more areas: viral transduction/transfection approaches, RNA and protein analysis such as Western Blot, ELISA and qRT-PCR, FACS, mammalian cell-based assays (e.g. binding and blocking assays, reporter assays, signalling assays) would be advantageous

To apply for this position, please send a full CV along with a cover letter to careers@engitix.com.