Associate Scientist/Scientist – Histology/IHC Specialist

04th February 2022

Engitix uses proprietary decellularisation technologies to expand cells in 3D culture. Unlike traditional decellularisation technologies which generate extracellular matrix (ECM) products from animal tissue, the Engitix 3D Tissue Engineering System produces human ECM scaffolds which retain the biophysical and biochemical properties of the healthy or diseased donor organ ECM. These ECM scaffolds are then used to develop in vitro disease models for the discovery and validation of novel therapeutic targets and to identify effective therapeutics for fibrosis and solid tumours.

Key Responsibilities

  • Perform paraffin embedding, sectioning and basic histo-chemical staining to support multiple projects
  • Perform IHC based assays to support target confirmation and validation workflows
  • Expected to work independently liaising closely with colleagues within and across functional groups to ensure deadlines are met
  • Be responsible for monitoring and maintaining equipment and levels of consumables within the histology facility

Qualifications and Competencies

Required

  • A BSC / MSc with experience in Biomedical sciences, Biochemistry, Biotechnology or related disciplines
  • Excellent working experience basic histology techniques including microtomy, paraffin embedding and histo-chemical staining
  • Knowledge and experience in performing manual and automated immunohistochemistry based assays
  •  2 – 3 years’ experience performing laboratory research in either a biotech/pharma /CRO environment
  • The post holder should be good at troubleshooting, methodical, well organised, and able to pay close attention to detail, particularly with regards to record keeping
  • Work flexibly across multiple sites in a fast-paced industrial research environment as a team player
  • Excellent communication skills in written and verbal English

Desirable

  • Understanding of basic normal liver histology
  • Knowledge of histological scoring systems and methods of quantification
  • Knowledge and experience in additional tissue-based assays

To apply for this position, please send a full CV along with a cover letter to careers@engitix.com.